Refractory peptic ulcers are defined as ulcers that do not heal completely after 8 to 12 weeks of standard anti-secretory drug treatment. - Blood supply. Post on 13-Nov-2014. Generally peptic ulcer disease is encountered more frequently in males (M:F 3:1) 2and usually in the older population. Chronic use of NSAIDS (aspirin, ibuprofen, naproxen) weakens and thins the mucosal lining of the stomach and duodenum and greatly contributes to the formation of breaks in the protective lining. Document presentation format: On-screen Show (4:3) Company: org Other titles: Arial Wingdings Times New Roman Network 1_Network 2_Network 3_Network 4_Network 5_Network 6_Network 7_Network 8_Network 9_Network 10_Network 11_Network Peptic Ulcer Disease Definition Peptic Ulcers: Gastric & Dudodenal PUD Demographics Comparing Duodenal and Gastric Ulcers Duodenal Ulcers Gastric Ulcers … Etiology and pathophysiology of peptic ulcer. Gastric ulcer formation may be related to back-diffusion of acid through damaged mucosa. Antiulcer pharmacology. Peptic ulcers occur when acid in the digestive tract eats away at the inner surface of the stomach or small intestine. The clinical presentation, diagnosis, treatment for gastric vs. duodenal ulcers are different. (Uphold Graham, 2003) 3 Peptic Ulcers Gastric Dudodenal 4 PUD Demographics . The most common symptom of a peptic ulcer is stomach pain.Peptic ulcers include: 1. Risk factors include 2,4: 1. PEPTIC ULCER DISEASE Hannah Vawda FY1 * * * * * * * * * * * * * * 1 calcium antagonists, nitrates, theophyllines, bisphosphonates, steroids and NSAIDs. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. Patient Case Presentation A 61-year-old American woman was referred to a Gastroenterology Clinic from primary care provider due to consistent discomfort and significant weight loss. See our Privacy Policy and User Agreement for details. As for symptomatic presentation of peptic ulcer (Figure 1), stomach pain was the most frequently recorded symptom (88.4%) followed by hyperacidity (60.6%), underweight (57.4%), vomiting (40.6%), loss of appetite (39.4%) while vomiting of blood was found to be least frequent (7.7%). [1] They newly began in around 53 million people in 2014 [4] About 10% of people develop a peptic ulcer at some point in their life [5]. The acid can create a painful open sore that may bleed. Raika Jamali M.D. PDF | On May 30, 2019, Monjur Ahmed published Peptic Ulcer Disease | Find, read and cite all the research you need on ResearchGate Complications and treatment. But by region or area peptic ulcers are three types and are-Oesophageal Ulcer, Gastric Ulcer, Duodenal Ulcer. Most Popular; Study; Business; Design; Data & Analytics; Explore all categories; peptic ulcer disease ppt. Peptic Ulcer • An Ulcer is … Erosion in the lining of the stomach or the first part of the small intestine, an area called the duodenum. 2. Peptic Ulcer Disease (PUD) by FreeMedsite May 21, 2020 May 21, 2020. In the latter scenario, failure of medical management not uncommonly leads to surgical intervention. Location and symptoms. Title: Peptic Ulcer Disease 1 Peptic Ulcer Disease . out of 18. In peptic ulcer disease, excessive secretion of hydrochloric acid diminishes the protective effects of mucus secretion and acid neutralization. Interestingly, those at the highest risk of contracting peptic ulcer disease are those generations born around the middle of the 20th century. He or she may look for H. pylori using a blood, stool or breath test. Epidemiology • Peptic ulcers are common and it has been estimated that up to 10% of the population has an ulcer and annual incidence of symptomatic peptic ulcer about 0.3%. Peptic ulcers are present in around 4% of the population. Looks like you’ve clipped this slide to already. The primary cause of peptic ulcer disease (approx. Epidemiology. They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990 [6]. Cont’d. of Surgery; 2 Historical Aspects. Dr. J.H. [1] They newly began in around 53 million people in 2014 [4] About 10% of people develop a peptic ulcer at some point in their life [5]. Peptic ulcer. Pantoprazole sodium hydrate 718635-09-7-api, No public clipboards found for this slide. NSAIDs 3. corticosteroids 4. severe physiological stress/illness (e.g. It is possible to get an ulcer almost anywhere. Increased gastric acid secretion. Carrie Jones; 2 Definition. Gastric ulcer: It occurs in stomach particularly in lower half portion. for peptic ulcer in infected individuals ranges from 3% in the United States to 25% in Japan [14]. admission to intensive care) 5. The pain starts in the epigastrium but by the time of presentation in the emergency department, it is generalized and associated with diffuse peritonitis. Looks like you’ve clipped this slide to already. AIMST University, Malaysia. Faculty of Pharmacy, Gastric ulcer: It occurs in stomach particularly in lower half portion. Despite the popular belief that peptic ulcers are caused by spicy foods or stress, the reality is that most of the time, peptic ulcers are caused by infection with a bacterium called Helicobacter pylori or use of NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen; ulcers caused by NSAIDs are associated with increased risk of complications. 2009 Jan;33(1):80-5. doi: 10.1007/s00268-008-9796-1. Causes. The initial management of a stable patient with dyspepsia differs from the management of an unstable patient with upper gastrointestinal (GI) hemorrhage. Patients generally present with dyspepsia or peptic ulcer bleeding. Ulcers damage the mucosa of the alimentary tract, which extends through the muscularis mucosa into the sub mucosa or deeper. – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 419ae3-OGI0O Ulcers that form in the stomach are called gastric ulcers; in the duodenum, they are called duodenal ulcers. Gastric and duodenal ulcers usually cannot be differentiated based on history alone, although some findings may be suggestive. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. ‘ULCER’ simply means a break or lesion in the lining, mucous membrane or skin in any part of the body. The two major causes of PUD are Helicobacter pylori infection and NSAID usage. next. A peptic ulcer may be referred to as a gastric, duodenal, or esophageal ulcer, depending on its location. PEPTIC ULCER • Gastric ulcers occurs mostly in the lesser curvature of the stomach. A circumscribed ulceration of the gastrointestinal mucosa occurring in areas exposed to acid and pepsin and most often caused by Helicobacter pylori infection. Post on 13-Nov-2014. A peptic ulcer is an excavation that forms in the mucosal wall of the stomach, in the pylorus, in the duodenum, or in the esophagus. Chronic peptic ulcer (stomach) is a mucosal defect which penetrates the muscularis mucosae and muscularis propria, produced by acid-pepsin aggression. Title: Stomach and Duodenum Peptic Ulcer - Pathology, clinical features, management Author: Administrator Last modified by: KFH Created Date: 9/2/2002 4:01:47 PM – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 6d3260-NjAwO Blood tests are generally inaccurate a… Now customize the name of a clipboard to store your clips. At least one person in every ten is likely to have a Peptic Ulcer at one time or another. You can change your ad preferences anytime. Peptic ulcer is one of the common GI disorders. However, recurrence is common after treatment with H2 antagonists is stopped,Patients with NSAID-induced ulcers should be treated with PPIs, because these agents heal and prevent future ulcers better than H2 antagonists.Acute stress ulcers: These drugs are useful in managing acute … Peptic ulcer disease. The clinical presentation, diagnosis, treatment for gastric vs. duodenal ulcers are different. This can be confirmed with biopsies obtained at endoscopy and urea breath test, the combination of the two resulting in a detection rate of close to 100… Aims: Definition of peptic ulcer. Free + Easy to edit + Professional + Lots backgrounds. Chronic peptic ulcer it is caused by high chlorhydro-peptic gastric secretion, as a result of either parietal cell hyperplasia, excessive secretory response (i.e., psychological stress) or impaired inhibition of stimulatory mechanism such as gastrin release (as in chronic renal failure or hyperparathyroidism). Fig: Peptic ulcer disease Causes or Reasons for Peptic Ulcer Disease: The different causes for peptic ulcer are-Infection with Helicobacter pylori (H. Pylori), Use of painkillers called nonsteroidal anti-inflammatory drugs such as Ibuprofen, Aspirin, and Naproxen. 3. However, there are many differences between children and adults, especially in the areas of clinical presentation, the prevalences of diffe … In the latter scenario, failure of medical management not uncommonly leads to surgical intervention. next. Dordrecht, Kluwer Academic Publishers, 1991, pp 273–282. Ulcer occurring in either of these two sites is called peptic ulcer . Duodenal ulcer formation is related to hypersecretion of acid, possibly caused by overactive vagal stimulation. Patient Case Presentation A 61-year-old American woman was referred to a Gastroenterology Clinic from primary care provider due to consistent discomfort and significant weight loss. Some common types of peptic ulcer are: Duodenal ulcer: It occurs in duodenum just after the pylorus of the stomach. Sina Hospital. A ‘Peptic Ulcer’ is any sort of ulcer that results from the action of stomach acid. See our User Agreement and Privacy Policy. They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990 [6]. Peptic Ulcer. Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. There are various risk factors for the development of peptic ulcer disease, but the most important ones are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs). Your doctor may recommend tests to determine whether the bacterium H. pylori is present in your body. Its also known as acid peptic disease (APD) Patho physiology Of Peptic Ulcer. You can change your ad preferences anytime. Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine. Epidemiology. - Blood supply. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The ulcer is located on the jejunal side of the anastomosis, which is exposed to the chlorhydro-peptic secretion. Zollinger-Ellison syndrome The majority of cases are due to infection with Helicobacter pylori. Perforated and bleeding peptic ulcer clinical practice guidelines were released in January 2020 by the World Society of Emergency Surgery. Clipping is a handy way to collect important slides you want to go back to later. Home; Documents; Peptic Ulcer Disease Ppt; prev. Definition: Peptic ulcer is a hole or open sore in the lining of the stomach, duodenum (beginning of the small intestine) or oesophagus. the duodenum) may be called a duodenal ulcer. Tehran University of Medical Sciences Ulcers: breaks in the mucosal surface >5 mm, with depth to the submucosa Health care costs of ~$10 billion / year in the US; Despite the constant attack on the gastroduodenal mucosa by noxious agents (acid, pepsin, bile acids, pancreatic enzymes, drugs, and … Definition of peptic ulcer. Most Popular; Study; Business; Design; Data & Analytics; Explore all categories; peptic ulcer disease ppt. The prevalence of peptic ulcer and gastric ulcer was 9.4% and 4.7% in Taiwan, respectively [1,2]. Precautions. Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). Ulcer may occur anywhere in the body. Peptic ulcer disease (PUD) is defined as a mucosal break larger than 3 mm in depth in the stomach or duodenum. PEPTIC ULCER disease (PUD) Dr. Gehan Mohamed Dr. Abdelaty Shawky Learning Objectives Recognize the typical clinical presentation and risk factors for peptic ulcer ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 42ee4e-MWJiN 5. Title: Peptic Ulcer Disease: 1 Peptic Ulcer Disease. The genetics of peptic ulcer disease. Perforated peptic ulcer: clinical presentation, surgical outcomes, and the accuracy of the Boey scoring system in predicting postoperative morbidity and mortality World J Surg. peptic ulcer disease.PPT 1. A circumscribed ulceration of the gastrointestinal mucosa occurring in areas exposed to acid and pepsin and most often caused by Helicobacter pylori infection. Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. But by region or area peptic ulcers are three types and are-Oesophageal Ulcer, Gastric Ulcer, Duodenal Ulcer. Clinical Complications The acute clinical complication of ulcers is bleeding and approximately occurs in 15%-20% of . Background: A prospective study was performed in order to assess the clinical presentation of peptic ulcer. Peptic Ulcer Disease: Introduction Peptic ulcer disease represents a serious medical problem. Performing surgery as soon as possible, particularly in patients with delayed presentation or those older than 70 years. Chronic symptoms include ulcer perforation and stricture formation. Ulcer margins are regular, slightly elevated due to adjacent chronic gastritis. Treatment of peptic ulcers varies depending on the etiology and clinical presentation (see Guidelines). Barnard ; Dept. Approximately 500,000 new cases are reported each year, with 5 million people affected in the United States alone. Now customize the name of a clipboard to store your clips. The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. Both types are referred to as peptic ulcers. To show you more relevant ads your LinkedIn profile and activity Data to personalize ads to. In 301,000 deaths in 1990 [ 6 ] usually in the latter,... Pantoprazole sodium hydrate 718635-09-7-api, No public clipboards found for this slide already! 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